Read-only view of a live SciFlow workflow — this is the actual pipeline that produced these results, not a mockup. RNA-seq Demo — Airway Steroid Response (Himes 2014). Open any stage to inspect its parameters, command, versions, inputs and outputs.
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Created May 08, 2026 at 12:42
Mike Love persona demo — canonical bulk RNA-seq DE pipeline on the Himes 2014 airway smooth muscle dataset (GSE52778 / SRP033351). PMID 24926665. 4 donors × (untreated vs dexamethasone), 8 paired-end Illumina HiSeq samples. Pipeline: Salmon quant (8 samples, auto-detect index) → bulk_de (tximport + DESeq2 + apeglm shrinkage + BH FDR). Design formula: ~ donor + treatment Contrast: treatment_dex_vs_untreated Data: The 8 FASTQ pairs and the GENCODE v44 Salmon index are pre-staged in MinIO under projects/rnaseq-demo-airway-himes2014/. The salmon_quant stages have forward_reads / reverse_reads set to the per-sample filenames and will find the salmon_index/ directory automatically from the input manifest.